Abstract: The 2010 work programme is the first to fall under the EMCDDA’s new three-year strategy and work programme (2010–12). In terms of substantive technical activities, the three-year strategy aims to consolidate the core data sets held by the agency and enable more complex analysis of them. It also scales up and develops some new areas of strategic importance. This means that 2010 will necessarily be a formative and exploratory year during which the structures and approaches needed to deliver the objectives set out in the work programme are put in place.