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Author |
Straiker, Alex; Stella, Nephi; Piomelli, Daniele; Mackie, Ken; Karten, Harvey J.; Maguire, Greg |
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Title |
Cannabinoid CB1 receptors and ligands in vertebrate retina : localization and function of an endogenous signaling system |
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Journal Article |
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Year |
1999 |
Publication |
Proceedings of the National Academy of Sciences of the United States of America |
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Volume  |
96 |
Issue |
25; 07.12.1999 |
Pages |
14565-14570 |
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Keywords |
cannabinoids; receptor ligand binding; retina; research |
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Abstract |
CB1, a cannabinoid receptor enriched in neuronal tissue, was found in high concentration in retinas of rhesus monkey, mouse, rat, chick, goldfish, and tiger salamander by using a subtype-specific polyclonal antibody. Immunolabeling was detected in the two synaptic layers of the retina, the inner and outer plexiform layers, of all six species examined. In the outer plexiform layer, CB1 was located in and/or on cone pedicles and rod spherules. Labeling was detected in some amacrine cells of all species and in the ganglion cells and ganglion cell axons of all species except fish. In addition, sparse labeling was found in the inner and/or outer segments of the photoreceptors of monkey, mouse, rat, and chick. Using GC/MS to detect possible endogenous cannabinoids, we found 3 nmol of 2-arachidonylglycerol per g of tissue, but no anandamide was detectable. Cannabinoid receptor agonists induced a dramatic reduction in the amplitude of voltage-gated L-type calcium channel currents in identified retinal bipolar cells. The presence and distribution of the CB1 receptor, the large amounts of 2-arachidonylglycerol found, and the effects of cannabinoids on calcium channel activity in bipolar cells suggest a substantive role for an endogenous cannabinoid signaling system in retinal physiology, and perhaps vision in general. |
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English |
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50-aw |
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59526 |
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various |
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Express Nr. 4/02 |
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Journal Article |
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2002 |
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Express : die Zeitschrift des Südhang |
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95 |
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1 |
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16 |
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treatment and maintenance; residential facility; addiction; AOD dependence; alcohol; Switzerland; Berne (canton); Kirchlindach; newsletter |
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Südhang |
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Kirchlindach |
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German |
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50-12341 |
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60894 |
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various |
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Express Nr. 3/02 |
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Journal Article |
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2002 |
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Express : die Zeitschrift des Südhang |
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95 |
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1 |
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16 |
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treatment and maintenance; residential facility; addiction; AOD dependence; chemical addiction; alcohol; quality; Switzerland; Berne (canton); Kirchlindach; newsletter |
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Südhang |
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Kirchlindach |
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German |
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50-12331 |
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60884 |
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various |
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Express Nr. 2/02 |
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Journal Article |
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2002 |
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Express : die Zeitschrift des Südhang |
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95 |
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1 |
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16 |
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treatment and maintenance; residential facility; addiction; AOD dependence; chemical addiction; alcohol; Switzerland; Berne (canton); Kirchlindach; newsletter |
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Südhang |
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Kirchlindach |
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German |
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Call Number |
50-12322 |
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60875 |
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various |
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Title |
Express Nr. 1/02 |
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Journal Article |
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Year |
2002 |
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Express : die Zeitschrift des Südhang |
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Volume |
95 |
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1 |
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16 |
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treatment and maintenance; residential facility; addiction; AOD dependence; chemical addiction; alcohol; public health care financing; administration and management; Switzerland; Berne (canton); Kirchlindach; newsletter |
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Südhang |
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Kirchlindach |
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German |
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Call Number |
50-12313 |
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60866 |
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Author |
Stricker, Hans Rudolf |
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Title |
Standpunkt : Der Ritalinkonsum steigt weiter an : Was sind die Ursachen, welche Massnahmen sind zu ergreifen? |
Type |
Journal Article |
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Year |
2013 |
Publication |
Schweizerische Ärztezeitung |
Abbreviated Journal |
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Volume |
94 |
Issue |
15; 10.04.2013 |
Pages |
575-577 |
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Keywords |
AOD consumption; AOD dependence; licit drug; brain; doping; methylphenidate; ritalin; physician; attitude toward AOD; continuing education; statistical data; Switzerland; commentary |
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Abstract |
Mit welchen geeigneten Massnahmen kann der zunehmende Verbrauch von Methylphenidat eingeschränkt werden? So die Ausgangsfrage dieses Beitrags, dessen Autor qualifizierte Fachleute für ADHS fordert, die klare Diagnosen stellen und mit individuellen Therapieplänen arbeiten können. Von den Fachgesellschaften werden neue Richtlinien verlangt. Le méthylphénidate (par ex. Ritaline) est de plus en plus employé dans beaucoup d’affections. Hormis le trouble du déficit de l’attention/hyperactivité (TDA/H), il est utilisé comme stimulant du cerveau et, plus rarement, pour de nombreux autres troubles physiques et psychiques. Pour contenir cette augmentation, des mesures appropriées sont nécessaires. Premièrement, nous avons besoin de davantage de spécialistes du TDA/H qualifiés qui posent des diagnostics clairs et travaillent avec des plans thérapeutiques personnalisés. Deuxièmement, les sociétés de discipline médicale et les associations professionnelles sont appelées à rédiger de nouvelles directives ciblées dans ce domaine, contenant notamment des dispositions en matière de formation continue, afin de garantir une prise en charge de qualité aux patients atteints de TDA/H. Enfin, il est important que chaque médecin connaisse ses limites et qu’il ne diagnostique et ne traite sous sa propre responsabilité que les affections pour lesquelles il a été formé et dans lesquelles il a acquis de l’expérience sous la supervision de spécialistes. |
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German |
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0036-7486; 1424-4004 |
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Seulement resumé en français |
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Call Number |
50-13011 |
Serial |
60012 |
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Author |
Ott, Regula; Biller-Andorno, Nikola |
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Title |
La signification du neuroenhancement dans la pratique médicale |
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Journal Article |
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Year |
2013 |
Publication |
Bulletin des médecins suisses |
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Volume |
94 |
Issue |
13-14; 27.03.2013 |
Pages |
504-506 |
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Keywords |
research chemical; designer drug; treatment-provider-patient relations; physician; psychotherapy; psychiatric care; statistical data; survey |
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Abstract |
Présentation des résultats de l’étude “La signification du neuroenhancement pour les praticiennes et praticiens des domaines de la psychiatrie/psychothérapie et de la médecine de premier recours”, qui a visé à mieux comprendre les expériences et la position des médecins confrontés à des demandes pour des produits de neuroenhancement dans leurs cabinets. |
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French |
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ISSN |
1661-5948; 1424-4012 |
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Notes |
Auch auf Deutsch vorhanden: 50-12942 |
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Call Number |
50-12943 |
Serial |
60003 |
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Author |
Ott, Regula; Biller-Andorno, Nikola |
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Title |
Die Bedeutung des Neuroenhancements in der ärztlichen Praxis |
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Journal Article |
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Year |
2013 |
Publication |
Schweizerische Ärztezeitung |
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Volume |
94 |
Issue |
13-14; 27.03.2013 |
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504-506 |
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Keywords |
research chemical; designer drug; treatment-provider-patient relations; physician; psychotherapy; psychiatric care; statistical data; survey |
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Abstract |
Vorgestellt werden Ergebnisse der Studie “Bedeutung des Neuroenhancements für praktizierende ÄrztInnen im Bereich Psychiatrie und Psychotherapie sowie im Bereich der Hausarztmedizin”. Diese Untersuchung zielte darauf ab, Erfahrungen und Einstellungen von Ärzten, die in ihrer Praxis mit der Nachfrage nach Neuroenhancement-Produkten konfrontiert werden, besser zu verstehen. |
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German |
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0036-7486; 1424-4004 |
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Aussi disponible en français: 50-12943 |
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50-12942 |
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60002 |
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Author |
Carobbio Guscetti, Martina; Favrod-Coune, Thierry |
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Title |
La révision de la loi sur l'alcool – une pierre angulaire de la politique de santé |
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Journal Article |
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Year |
2013 |
Publication |
Bulletin des médecins suisses |
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94 |
Issue |
11; 13.03.2013 |
Pages |
411 |
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Keywords |
government and politics; laws and regulations; amendment; chemical addiction; alcohol; prevention; Switzerland |
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Abstract |
La révision totale de la loi sur l’alcool est actuellement débattue au Parlement. Les auteurs sont convaincus que cette loi n’atteindra son objectif en matière de santé publique que si les mesures de libéralisation proposées s’accompagnent d’autres mesures de prévention cohérentes. |
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French |
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1661-5948; 1424-4012 |
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Auch auf Deutsch vorhanden: 50-12809 |
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no |
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Call Number |
50-12810 |
Serial |
59996 |
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Author |
Carobbio Guscetti, Martina; Favrod-Coune, Thierry |
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Title |
Alkoholgesetzrevision – ein gesundheitspolitischer Meilenstein |
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Journal Article |
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Year |
2013 |
Publication |
Schweizerische Ärztezeitung |
Abbreviated Journal |
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Volume |
94 |
Issue |
11; 13.03.2013 |
Pages |
411 |
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Keywords |
government and politics; laws and regulations; amendment; chemical addiction; alcohol; prevention; Switzerland |
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Abstract |
Die Totalrevision des Alkoholgesetzes befindet sich aktuell in parlamentarischer Beratung. Die Autoren sind überzeugt, dass diese ihr gesundheitspolitisches Ziel nur erreicht, wenn den vorgeschlagenen Liberalisierungsmassnahmen kohärente Präventionsmassnahmen zur Seite gestellt werden. |
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German |
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0036-7486; 1424-4004 |
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Aussi disponible en français: 50-12810 |
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Call Number |
50-12809 |
Serial |
59995 |
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