Coste, J. - M., Kummer, J. - A., Kraemer, M., & Porchet, P. - A. (2008). Quelle évolution pour un patient substitué à la méthadone au long cours? Revue médicale suisse, 4(15.10.2008), 2225–2228.
Abstract: Le Drop-in de Neuchâtel propose des cures de substitution à la méthadone depuis 1975. Dans cette étude, nous analysons l’évolution de 119 patients en traitement sur une période de dix ans. Nos résultats confirment que les traitements de substitution sont souvent de longue durée (56% les maintiennent à dix ans) et qu’ils peuvent être arrêtés avec succès par certains (29%). Pour les patients qui maintiennent la méthadone au long cours, on observe une stabilisation globale de leur situation médico-psycho-sociale. Les résultats sont probants en ce qui concerne la diminution de la consommation d’héroïne et de la criminalité. Toutefois, le taux de réinsertion professionnelle est faible et on observe pour 30% d’entre eux, une dégradation lente de la santé physique, surtout en lien avec les maladies chroniques (VIH, VHC) et les habitudes de vie (consommation inappropriée d’alcool, tabagisme…).
Keywords: methadone; heroin-assisted treatment; evaluation; AOD consumption; criminality; social integration; work; communicable disease; study; statistical data; Switzerland; Neuchâtel; Drop-In (body)
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Herrlin, K., Segerdahl, M., Gustafsson, L. L., & Kalso, E. (2000). Methadone, ciprofloxacin, and adverse drug reactions . The Lancet, 356(9247; 16.12.2000), 2069–2070.
Abstract: Ciprofloxacin, given to a patient successfully treated with methadone for more than 6 years, caused profound sedation, confusion, and respiratory depression. We suggest that this was caused by ciprofloxacin inhibition of CYP1A2 and CYP3A4 activity, two of the cytochrome p450 isozymes involved in the metabolism of methadone.
Keywords: treatment and maintenance; methadone; ciprofloxacin; adverse drug effect
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various. (1992). Needlestick injury (Letters to the Editor). The Lancet, 340(07.11.1992), 1166–1167.
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Nixon, A. D., Law, R., Officer, J. A., Cleland, J. F., & Goldwater, P. N. (1986). Methods and devices : simple device to prevent accidental needle-prick injuries. The Lancet, (19.04.1986), 888–889.
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Jürgens, R. (1994). La prévention prise au sérieux: remise de seringues dans une prison suisse. Bulletin canadien VIH/sida et droit, 1(1), 1–3.
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Schaaf, S. (1996). Spritzenautomaten : die Erfahrungen der Pionierjahre : Studie zu Spritzen- und Flashbox-Automaten. Spectra : Gesundheitsförderung und Prävention, 5(09/1996), 4.
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McCarthy, M. (1994). LA law and clean needles. The Lancet, 344(8925; 17.09.1994), 810.
Abstract: Reports that Los Angeles, California Mayor Richard J. Riordan has declared a local state of emergency to the spread of AIDS and HIV infection. State crackdown on the distribution of clean needles to drug users; Riordan’s support for responsible needle-exchange programs.
Keywords: harm reduction
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Cox, G. M., Lawless, M. C., Cassin, S. P., & Geoghegan, T. W. (2000). Syringe exchanges : a public health response to problem drug use. Irish Medical Journal, 93(5), 143–146.
Abstract: This paper presents the findings of the first ever Irish follow-up study to establish the effectiveness of syringe exchanges as a harm reduction strategy in the context of public health. The study was conducted in collaboration with 370 injecting drug users who attended the Merchant’s Quay Project’s Health Promotion Unit between May 1st 1997 and October 31st 1998. Data was collected from respondents by means of a structured interview at first visit and three-months after initial contact. Evidence from the study demonstrates that syringe exchanges play an important contributing role in significantly reducing the numbers reporting both the use of heroin as a primary drug (n=41; McNemar x2=10.1;p<0.01), and its frequency of use (n=70; McNemar x2=4.13;p<0.05) at follow-up. Moreover, there were significant reductions in the reported borrowing (n=60; McNemar x2=10.1;p<0.01) and lending (n=42: McNemar x2=7.9;p<0.01) of used injecting equipment. There was however no significant change in the reported sharing of injecting paraphernalia or in levels of reported condom use. The results of this study illustrate that low threshold services such as the Health Promotion Unit have the ability to attract injecting drug users not in contact with other drug treatment services. Furthermore, this type of service has been shown to be effective in maintaining contact with injecting drug users and promoting safer drug use among attendees. Even though the distribution of sterile injecting equipment reduces the situational sharing, this is hampered by the limited availability of sterile injecting equipment in Dublin. There is a need to continue to develop strategies to prevent HIV and hepatitis C transmission. One such approach would be to develop effective outreach as a means of reaching greater numbers of drug users earlier in their injecting histories. Other areas for future HIV and HCV prevention include discouraging the transition from smoking to injecting, and among those who inject, encouraging further reductions in sharing, sustaining risk reduction over time, and encouraging the adoption of safer sexual behaviour.
Keywords: harm reduction
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Loosen, W. (2001). Qualitätsstandards in der europäischen Drogenhilfe : eine kritische Bestandsaufnahme. Konturen : Fachzeitschrift zu Sucht und sozialen Fragen, 22, 31–33.
Keywords: quality control
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Callégari, J. - P. (1999). Qualité et communication : introduction. Communication et organisation, (15), 2.
Keywords: quality control
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