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Author |
Hüsgen, Hans-A. |
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Akzeptanzorientierung in der Drogenpolitik – niedrigschwellige und höher-schwellige Drogenarbeit – laudatio et promotio = Orientation towards acceptance in drug policy : low-threshold and higher-threshold drug work – laudatio et promotio |
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Journal Article |
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Year |
2011 |
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Akzeptanzorientierte Drogenarbeit = Acceptance-oriented drug work |
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8 |
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18.10.2011 |
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44-47 |
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AOD dependence; AOD abstinence; history; harm reduction; INDRO (body) |
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German |
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1861-0110 |
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50-12285 |
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59969 |
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Author |
Kühne, René; Rapold, Roland |
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Title |
Der Bezug von Methylphenidat in der Schweiz : nicht alarmierend – Fragen stellen sich dennoch |
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Journal Article |
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Year |
2011 |
Publication |
Schweizerische Ärztezeitung |
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Volume |
92 |
Issue |
34; 08/2011 |
Pages |
1295-1299 |
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Keywords |
methylphenidate; Ritalin; prescription drug; general practitioner; child; adolescence; Switzerland |
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Der steigende Konsum von Methylphenidat in Zusammenhang mit ADHS wird in der Öffentlichkeit zunehmend diskutiert. Wie steht es um Fehldiagnosen und Missbrauch? In der vorgestellten Arbeit wurden die Verschreibungen und Abgaben auf Basis der bei der Krankenversicherung elektronisch erfassten Medikamentenbezüge für die Periode 2006 bis 2009 untersucht. |
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0036-7486 (Print); 1424-4004 (Online) |
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50-12105 |
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59953 |
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Author |
Dwight, Rodrick |
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Title |
Le dopage au travail se banalise |
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Journal Article |
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Year |
2011 |
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Revue d’information sociale |
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19.04.2011 |
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4 |
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AOD consumption; doping; workplace context; antianxiety tranquilizers; Switzerland |
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Dans notre société, la consommation de produits psychotropes s’est modifiée. Aujourd’hui, de nombreuses personnes prennent des drogues non pas parce qu’elles se sentent forcément mal, mais pour aller « un peu mieux », pour se sentir « mieux que bien » : être performant, supporter l’ennui, s’adapter à un environnement social ou professionnel difficile. |
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French |
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50-11882 |
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59947 |
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Author |
Ansermot, Nicolas; Albayrak, Özgür; Schläpfer, Jürg; Crettol, Séverine; Croquette, Marina; Bourquin, Michel; Déglon, Jean-Jacques; Faouzi, Mohamed; Scherbaum, Norbert; Eap, Chin B. |
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Title |
Substitution of (R,S)-methadone by (R)-methadone : impact on QTc interval |
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Journal Article |
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Year |
2010 |
Publication |
Archives of Internal Medicine |
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Volume |
170 |
Issue |
6 |
Pages |
529-536 |
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Keywords |
methadone; opioids in any form; narcotic analgesics; drug substitution therapy; empirical study; statistical data |
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Abstract |
BACKGROUND: Methadone is administered as a chiral mixture of (R,S)-methadone. The opioid effect is mainly mediated by (R)-methadone, whereas (S)-methadone blocks the human ether-à-go-go-related gene (hERG) voltage-gated potassium channel more potently, which can cause drug-induced long QT syndrome, leading to potentially lethal ventricular tachyarrhythmias. METHODS: To investigate whether substitution of (R,S)-methadone by (R)-methadone could reduce the corrected QT (QTc) interval, (R,S)-methadone was replaced by (R)-methadone (half-dose) in 39 opioid-dependent patients receiving maintenance treatment for 14 days. (R)-methadone was then replaced by the initial dose of (R,S)-methadone for 14 days (n = 29). Trough (R)-methadone and (S)-methadone plasma levels and electrocardiogram measurements were taken. RESULTS: The Fridericia-corrected QT (QTcF) interval decreased when (R,S)-methadone was replaced by a half-dose of (R)-methadone; the median (interquartile range [IQR]) values were 423 (398-440) milliseconds (ms) and 412 (395-431) ms (P = .06) at days 0 and 14, respectively. Using a univariate mixed-effect linear model, the QTcF value decreased by a mean of -3.9 ms (95% confidence interval [CI], -7.7 to -0.2) per week (P = .04). The QTcF value increased when (R)-methadone was replaced by the initial dose of (R,S)-methadone for 14 days; median (IQR) values were 424 (398-436) ms and 424 (412-443) ms (P = .01) at days 14 and 28, respectively. The univariate model showed that the QTcF value increased by a mean of 4.7 ms (95% CI, 1.3-8.1) per week (P = .006). CONCLUSIONS: Substitution of (R,S)-methadone by (R)-methadone reduces the QTc interval value. A safer cardiac profile of (R)-methadone is in agreement with previous in vitro and pharmacogenetic studies. If the present results are confirmed by larger studies, (R)-methadone should be prescribed instead of (R,S)-methadone to reduce the risk of cardiac toxic effects and sudden death. |
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0003-9926 |
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Call Number |
50-11821 |
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59945 |
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Author |
Dolan, Kate; Kimber, Jo; Fry, Craig; Fitzgerald, John L.; McDonald, David; Trautmann, Franz |
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Title |
Harm reduction digest 10 : Drug consumption facilities in Europe and the establishment of supervised injecting centres in Australia |
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Journal Article |
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Year |
2000 |
Publication |
Drug and alcohol review |
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Volume |
19 |
Issue |
3 |
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337-346 |
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Keywords |
harm reduction; contact center; injection room; Europe; Australia |
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0959-5236 |
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50-11813 |
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59944 |
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Author |
Liddle, Howard A. |
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Title |
Multidimensional family therapy : a science-based treatment system |
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Journal Article |
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Year |
2010 |
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The Australian and New Zealand Journal of Family Therapy |
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31 |
Issue |
2 |
Pages |
133-148 |
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adolescent; AOD abuse; family therapy; treatment and maintenance; treatment method; juvenile delinquency; research |
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Abstract |
MDFT is a family-based intervention for adolescent substance abuse and associated mental health and behavioural problems (Liddle, 2010). Integrative in several ways, MDFT uses an ecological or contextual conceptual framework to understand the developmental tasks of teens and their families. Research-derived knowledge about risk and protective factors, and proximal causes, correlates and contributors to adolescent drug and related problems inform clinical thinking and interventions with every case. A multisystems approach, MDFT assesses and intervenes in four areas: (1) the adolescent as an individual and a member of a family and peer network; (2) the parent(s), both as individual adults and in his or her role as mother, father or caregiver; (3) the family environment and family relationships, as manifested in day-to-day family transactional patterns; and (4) extrafamilial sources of influence such as peers, school and juvenile justice. Interventions are made within and coordinated across domains. Progress in one area or with one person has implications for and use in others. Individual meetings with parent(s) and teen set the stage for family sessions, and family meetings may offer content and new outcomes that need to be brought to extrafamily meetings with juvenile justice or school personnel. MDFT was developed and tested as a treatment system rather than a one-size-fits-all approach. A treatment system offers different versions of a clinical model that vary according to factors such as clinical sample characteristics (older versus younger adolescents, juvenile justice involved versus no involvement in juvenile justice systems), and treatment parameters (type of clinical setting and treatment dose). |
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0814-723x |
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50-11758 |
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59930 |
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Author |
Merzel, Cheryl; D'Afflitti, Joanna |
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Title |
Reconsidering community-based health promotion : promise, performance, and potential |
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Journal Article |
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Year |
2003 |
Publication |
American journal of public health : official journal of the American Public Health Association |
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93 |
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4; 04/2003 |
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557-574 |
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health promotion; communicable disease; HIV infection; community-based prevention; United States |
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Contemporary public health emphasizes a community-based approach to health promotion and disease prevention. The evidence from the past 20 years indicates, however, that many community-based programs have had only modest impact, with the notable exception of a number of HIV prevention programs. To better understand the reasons for these outcomes, we conducted a systematic literature review of 32 community-based prevention programs. Reasons for poor performance include methodological challenges to study design and evaluation, concurrent secular trends, smaller-than-expected effect sizes, limitations of the interventions, and limitations of theories used. The effectiveness of HIV programs appears to be related in part to extensive formative research and an emphasis on changing social norms |
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0090-0036 (Print); 1541-0048 (Online) |
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50-11667 |
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59924 |
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Matthews, Kent; Shepherd, Jonathan; Sivarajasingham, Vaseekaran |
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Violence-related injury and the price of beer in England and Wales |
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Journal Article |
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2006 |
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Applied economics |
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38 |
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6 |
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661-670 |
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alcohol product; beer; price and pricing; AOD price; AODR violence; injury; emergency care; economics; socioeconomic differences; United Kingdom; England; Wales |
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The paper examines the influence of the real price of beer on violence-related injuries across the economic regions in England and Wales. The data are monthly frequency of violent-injury collected from a stratified sample of 58 National Health Service Emergency Departments 1995-2000. An econometric model based on economic, socio-demographic and environmental factors was estimated using panel techniques. It is shown that the rate of violence-related injury is negatively related to the real price of beer, as well as economic, sporting and socio-demographic factors. The principal conclusion of the paper is that the regional distribution of the incidence of violent injury is related to the regional distribution of the price of beer. The major policy conclusion is that increased alcohol prices would result in substantially fewer violent injuries and reduced demand on trauma services. |
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0003-6846; 1466-4283 |
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Call Number |
50-11642 |
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59921 |
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Author |
Keppler, Karlheinz; Stöver, Heino; Schulte, B.; Reimer, Jens |
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Title |
Prison Health is Public Health! : Angleichungs- und Umsetzungsprobleme in der gesundheitlichen Versorgung Gefangener im deutschen Justizvollzug : ein Übersichtsbeitrag |
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Journal Article |
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2010 |
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Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz |
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53 |
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2-3; 20.01.2010 |
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233-244 |
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health promotion; HIV infection; Aids; health care program or facility; prison; AOD dependence; reorganization; Germany |
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Auf Basis internationaler Standards orientiert sich die Gesundheitsversorgung Gefangener auch in Deutschland am „Äquivalenzprinzip“ (Gleichwertigkeit der medizinischen Versorgung innerhalb der Gefängnisse mit der im jeweiligen Land vorgehaltenen medizinischen Versorgung). Vor diesem Hintergrund werden anhand ausgewählter Gesundheitsprobleme nicht nur vereinzelte Angleichungs- und Umsetzungsprobleme in der Gesundheitsversorgung Gefangener verdeutlicht, sondern auch strukturelle Probleme benannt, die aus dem von der GKV entkoppelten Parallelsystem der gefängniseigenen „Gesundheitsfürsorge“ resultieren. Die vorliegende Übersichtsarbeit dient als Grundlage für Vorschläge zum Umdenken und zur Reorganisation der intramuralen Gesundheitsdienste. On the basis of international standards, health care in German prisons has been oriented along the principle of equivalence (equity of health care delivery for inmates compared with the health care delivery in the community). Against this background, selected health problems demonstrate not only isolated problems in adaptation and implementation of health care delivery, but also structural problems resulting from the parallel system of prison health care, which is separated from the general German health care insurance system. This review serves as a basis to present suggestions to rethink and reorganize prison-based health care services. |
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1436-9990 (print); 1437-1588 (online) |
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Preview article |
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50-11166 |
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59895 |
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Author |
Meyer, Roger E. |
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The disease called addiction : emerging evidence in a 200-year debate |
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1996 |
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The Lancet |
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347 |
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162-166 |
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addiction; history |
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0140-6736 |
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50-11023 |
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59892 |
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