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Author
Aguirre, J. C.; Del Arbol, J. L.; Raya, J.; Ruiz-Requena, M. E.; Rico Irles, J.
Title
Plasma β-endorphin levels in chronic alcoholics
Type
Journal Article
Year
1990
Publication
Alcohol
Abbreviated Journal
Volume
7
Issue
Pages
409-412
Keywords
AOD dependence; addiction; chemical addiction; alcohol; alcohol dependence; chronic drug effect; research; research chemical; journal article
Abstract
In order to test the possible relationship between the chronic consumption of alcohol and the opioid system, we have measured the plasmalevels of β-endorphin in a group of 31 alcoholic patients and compared the results with those of a control group of 16 subjects. Our results show that chronic consumption of alcohol induces a significant decrease in β-endorphin (β-end) plasmalevels regardless of either the disease suffered by the alcoholic patient or of the time of abstinence studied (one month maximum). Thus we believe that the β-end decrease may well be due to the patients’ alcoholism and that it might be mediated by the tetrahydroisoquinoline system, or be a cause of alcoholism rather than a consequence.
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English
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Conference
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no
Call Number
50-00009
Serial
59609
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